产品货号：
Z14094
中文名称：
DNMT3B抗体
英文名称：
Anti-DNMT3B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DNMT3B Antibody |
| 指标别名 | CMTDI1;CMTDIB;DI CMTB;DNM2;DYN2;dynamin 2;DYNII |
| 克隆性 | Polyclonal |
| 检验物种 | human,monkey,mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | DNMT3B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human DNMT3B recombinant protein (Position:E271-E853). |
| 实际分子量 | 96KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | DNA (cytosine-5-)-methyltransferase 3 beta,is an enzyme that in humans in encoded by the DNMT3B gene.CpG methylation is an epigenetic modification that is important for embryonic development,imprinting,and X-chromosome inactivation.Studies in mice have demonstrated that DNA methylation is required for mammalian development.This gene encodes a DNA methyltransferase which is thought to function in de novo methylation,rather than maintenance methylation.The protein localizes primarily to the nucleus and its expression is developmentally regulated.Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome.Eight alternatively spliced transcript variants have been described.The full length sequences of variants 4 and 5 have not been determined. |
| Uniprot ID | P50570 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | DNA methyltransferase 3 beta |
| 蛋白名全称 | DNA (cytosine-5)-methyltransferase 3B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 (ELISA)： 1:100～1000 Flow cytometry (FCM) 1～3μg/1×106 cells Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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